THE UTILITY OF OBJECTIVE, FUNCTIONAL METRICS IN EYE CARE
Patients with diabetic retinopathy can present difficult clinical questions, even to the most experienced experts. While measurements like vision loss signify disease progression, visual acuity gains do not necessarily correlate with improvement in structure or global function. Despite the array of diagnostic modalities available to you, very few deliver actionable information that is helpful in deciding if treatment is working, when to change course, or perhaps even when to cease treatment because risks outweigh the potential benefits.
As an objective measure of global retinal function loss and recovery,1-2 flicker electroretinography (ERG) provides information that helps inform treatment decisions in a number of pathologies including diabetic retinopathy (DR),1,3 branch (BRVO) and central retinal vein occlusion (CRVO),4,5 and uveitis,6 among others.
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1. Holm K, et al. Peripheral retinal function assessed with 30-Hz flicker seems to improve after treatment with Lucentis in patients with diabetic macular oedema. Doc Ophthalmol. 2015;131:43-51. 2. Yasuda S, et al. Flicker electroretinograms before and after intravitreal ranibizumab injection in eyes with central retinal vein occlusion. Acta Ophthalmol. 2015;93:e465-8. 3. Pescosolido N, et al. Role of Electrophysiology in the Early Diagnosis and Follow-Up of Diabetic Retinopathy. J Diabetes Res;2015:319692. 4. Noma H, et al. Association of electroretinogram and morphological findings in branch retinal vein occlusion with macular edema. Doc Ophthalmol. 2011;123:83-91. 5. Noma H, et al. Association of electroretinogram and morphological findings in central retinal vein occlusion with macular edema. Clin Ophthalmol. 2014;8:191-7. 6. Moschos MM, et al. Electrophysiological examination in uveitis: a review of the literature. Clin Ophthalmol. 2014;8:199-214.